RESULTS: ADRs of defibrase mainly included bleeding, urticaria, high fever, positive cutantest, liver function injury, ecchymoma, purpura haemorrhagica, incision hemorrhea, and arterial embolism. 结果:降纤酶所致不良反应主要有出血、荨麻疹、高热反应、皮肤试验阳性、肝功能损害、皮下血肿、血小板减少性紫癜、切口大出血以及动脉栓塞等。